General description
Mammals contain three main classes of histone H3 variants: the replicative histones (H3.1 and H3.2), the replacement histone (H3.3) and the centromeric histone (Cenp-A). Histone H3 is located on human chromosome 6p22.
Specificity
This antibody reacts to Histone H3 acetylated at Lysine 56 (K56ac). No cross reactivity with other acetylated Lysines in histone H3.
Immunogen
Synthetic peptide corresponding to the Acetyl-Histone H3 (Lys56)
Biochem/physiol Actions
Histone proteins are basic building blocks of chromatin. Histone H3 K27M mutations in adult cerebellar high-grade gliomas. It controls protein-protein interactions to induce binding of trans-acting factors that drive chromatin condensation.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Shipping Information:
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- UPC:
- 51311607
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- SAB5600015-100UG
- Temperature Control Device:
- Yes
