General description
A-kinase anchoring protein 79 (AKAP 79) is a scaffolding protein that resides predominantly in excitatory neuronal synapses. AKAP 79 interacts with membrane-associated guanylate kinase (MAGUK) to be used by glutamate receptors. AKAP 79 may also be involved with SAP97 and other large signaling complexes. AKAP 79 is essential for forskolin-induced up-regulation of L-current.
Specificity
This antibody recognizes AKAP 79 at the C-terminus.
Immunogen
KLH-conjugated linear peptide corresponding to the C-terminus of human AKAP 79.
Application
Detect AKAP 79 using this Anti-AKAP 79 Antibody validated for use in WB.
Quality
Evaluated by Western Blot in HEK293 cell lysate with overexpressed N-terminal Flag-AKAP79.
Western Blot Analysis: 1 µg/mL of this antibody detected AKAP 79 on 10 µg of HEK293 cell lysate with overexpressed N-terminal Flag-AKAP79.
Target description
~79 kDa observed.
AKAP79 migrates in WB with an apparent molecular weight of ~79 kDa Uncharacterized bands appear at ~35 kDa and ~13 kDa in some lysates.
Analysis Note
Control
HEK293 cell lysate with overexpressed N-terminal Flag-AKAP79
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: human. technique(s): western blot: suitable. NCBI accession no.: NP_004848. UniProt accession no.: P24588. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... AKAP5(9495). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 41116126
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- ABS102
