General description
Aldehyde dehydrogenase 1A1 (ALDH1A1) is also known as retinal dehydrogenase 1. It is thought to be a main converter of retinol to retinoic acid, which is very important in cell to cell signaling. ALDH1A1 may also be involved in inhibiting invasion in pancreatic cancer cells. More specifically, ALDH1A1 may regulate hematopoietic stem cell differentiation by disrupting the retinoid signaling.
Specificity
Other homologies: rat and mouse (91% sequence homology).
Immunogen
KLH-conjugated linear peptide corresponding to human Aldehyde dehydrogenase 1.
Application
Research Category
Stem Cell Research
This Anti-Aldehyde dehydrogenase 1 (ALDH1A1) Antibody is validated for use in WB for the detection of Aldehyde dehydrogenase 1 (ALDH1A1).
Quality
Evaluated by Western Blot in HepG2 cell lysate.
Western Blot Analysis: 0.05 µg/mL of this antibody detected Aldehyde dehydrogenase 1 on 10 µg of HepG2 cell lysate.
Target description
~54 kDa observed
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
HepG2 cell lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: human. packaging: antibody small pack of 25 . μ. g. technique(s): western blot: suitable. NCBI accession no.: NP_000680. UniProt accession no.: P00352. shipped in: ambient. storage temp.: 2-8°C. target post-translational modification: unmodified. Gene Information: human ... ALDH1A1(216). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 41141625
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- ABD12