General description

Androgen receptor (AR) is a receptor for the androgenic hormones testosterone or dihydrotestosterone and it is a member of the steroid superfamily of ligand-dependent transcription factors. In the absence of androgen, the unligated AR mainly locates in cytoplasm, but translocates to the nucleus upon binding to androgen. Truncated AR variants with loss of C-terminus are common in prostate cancer.

Immunogen

Synthetic peptide from the C-terminus of human androgen receptor protein.

Features and Benefits

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Physical form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.