General description

ANPA is a receptor for atrial natriuretic peptide. It exhibits guanylate cyclase activity on binding of ANF. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction. This Type I membrane protein belongs to the adenylyl cyclase class-4/guanylyl cyclase family and contains 1 protein kinase-like domain.

Immunogen

ANPA (NP_000897, 1-30)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ANPA.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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