General description

Adenomatous polyposis coli (APC) is a tumour suppressor gene. It is located on human chromosome 5q21.

Anti-APC Antibody detects endogenous levels of total APC protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human APC.

Immunogen Range: 2794-2843

Biochem/physiol Actions

Adenomatous polyposis coli (APC) plays an important role in cell division, adhesion and migration. Mutations in APC gene is associated with colorectal carcinomas.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.