General description
APS is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt lymphoma cell lines, it is tyrosine phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to Shc/Grb2.
Immunogen
APS (NP_066189, 256-289)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human APS.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
- UPC:
- 12352203
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- SAB1300902-100UG
- Product Size:
- 100/µG