General description
The water-specific channel Aquaporin 4 is located in various tissues including the gastro intestinal tract, kidney and brain. It is an osmoreceptor which regulates body water balance and mediates water flow within the central nervous system. The localization of AQ4 to astrocyte endfeet makes it an excellent marker for astrocyte distal processes.
Specificity
Recognizes Aquaporin 4.
The antibody has not yet been tested for cross-reactivity to other species. The immunogen shows 94% similarity to mouse, 88% to bovine, 86% to rabbit and 82% to human AQP4 (hAQP4).
Immunogen
Epitope: C-Terminus
Synthetic Linear Peptide
Application
Anti-Aquaporin 4 Antibody is an antibody against Aquaporin 4 for use in WB.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
Western Blotting: 0.5-1 μg/mL using Chemiluminescence technique.
Optimal working dilutions must be determined by end user.
Target description
~34 kDa
Linkage
Replaces: AB3068
Physical form
ImmunoAffinity Purified
Purified in PBS with 0.05% NaN3
Storage and Stability
Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
Analysis Note
Control
Tested on adult rat brain lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: human, mouse, rat. manufacturer/tradename: Chemicon®. . technique(s): western blot: suitable. NCBI accession no.: NM_001650.4, NM_004028.3. UniProt accession no.: P55087. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... AQP4(361). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51203104
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- AB2218
