Anti-ATP13A2 antibody produced in rabbit (C15-1315-550)

General description

ATP13A2 is a member of the P5 family of ATPases which function in the transport of inorganic cations.

ATPase type 13A2 (ATP13A2) is a neuronal P-type ATPAse. The gene is also referref as PARK9 (Parkinson′s disease 9).

Rabbit Anti-ATP13A2 antibody binds to human and mouse ATP13A2.

Application

Rabbit Anti-ATP13A2 antibody has been used for western blot assays.

Biochem/physiol Actions

Mutations in the gene encoding ATPase type 13A2 (ATP13A2) is implicated with a hereditary form of PD associated with dementia, known as Kufor-Rakeb syndrome (KRS). ATP13A2 shows elevated expression levels in brains of sporadic PD patients, suggesting a potential role in the more common forms of Parkinson′s disease.

Physical form

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source: rabbit. Quality Level: 200. conjugate: unconjugated. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. form: buffered aqueous solution. mol wt: antigen ~129 . kDa. species reactivity: mouse, human. enhanced validation: recombinant expression
Learn more about Antibody Enhanced Validation. concentration: ~1 . mg/mL. technique(s): western blot: 1-2 . μ. g/mL using mouse brain extract (S1 fraction), western blot: 2-4 . μ. g/mL using extract of HEk-293T cells expressing human ATP13A2. shipped in: dry ice. storage temp.: −. 20°C. target post-translational modification: unmodified. Gene Information: human ... ATP13A2(23400)
mouse ... Atp13a2(74772)
rat ... Atp13a2(362645). Storage Class Code: 10 - Combustible liquids. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US).