ANTI-BAALC ANTIBODY (C005B-241330)

General description

Brain and acute leukemia cytoplasmic protein (BAALC) interacts with CAMK2A in a synaptic role at postsynaptic lipid rafts. BAALC is expressed by neural, hematopoietic, normal early progenitor cells and in the most immature type of blasts in acute leukemia. Isoform 2 and isoform 6 are also expressed in the brain.

Specificity

This antibody recognizes the CAMK2A interaction domain of BAALC. This antibody should recognize all isoforms in uniprot.

Immunogen

Epitope: CAMK2A interaction domain

KLH-conjugated linear peptide corresponding to the CAMK2A interaction domain of human BAALC.

Application

Detect Brain & acute leukemia cytoplasmic protein using this rabbit polyclonal antibody, Anti-BAALC Antibody validated for use in western blotting.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Quality

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected BAALC in 10 µg of mouse brain tissue lysate.

Target description

~22 kDa observed. Uniprot describes 6 isoforms produced by alternative splicing at ~19 kDa, ~16 kDa, ~9 kDa, ~8 kDa and ~6 kDa

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Mouse brain tissue lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: rat, mouse. species reactivity (predicted by homology): human (based on 100% sequence homology), bovine (based on 100% sequence homology), porcine (based on 100% sequence homology). technique(s): western blot: suitable. NCBI accession no.: NP_079088. UniProt accession no.: Q8WXS3. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... BAALC(79870). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.

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