ANTI-BMPR-1A ANTIBODY (C15-1316-824)

General description

BMPR-1A (bone morphogenic protein receptor type 1A) signaling is known to be important for inner root sheath differentiation, hair follicle cycling and tooth development. Mutations in BMPR-1A are a common cause of juvenile polyposis syndrome (JPS). BMPR-1A is expressed in a high quantity during the formation of the primary and secondary palate and the loss of BMPR-1A could be a cause for the cleft palate birth defect.

Specificity

This antibody recognizes BMPR-1A at the extracellular domain.

Immunogen

Epitope: Extracellular domain

KLH-conjugated linear peptide corresponding to the extracellular domain of human BMPR-1A.

Application

Anti-BMPR-1A Antibody is an antibody against BMPR-1A for use in WB.

Research Category
Stem Cell Research

Research Sub Category
Kinases & Phosphatases

Quality

Evaluated by Western Blot in NIH/3T3 cell lysate.

Western Blot Analysis: 0.1 µg/mL of this antibody detected BMPR-1A on 10 µg of NIH/3T3 cell lysate.

Target description

~75 kDa observed. The calculated molecular weight is 67 kDa; however, BMPR-1A has been shown as a ~77 kDa band in western blots (Koenig, B., et al. (1994). Molecular and Cellular Biology. 14(9):5961-5974).

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
NIH/3T3 cell lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: rat, human, mouse. technique(s): western blot: suitable. NCBI accession no.: NP_004320. UniProt accession no.: P36894. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... BMPR1A(657). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.