Anti-C1QA antibody produced in chicken

Immunogen

Complement C1q subcomponent subunit A native protein.

Immunogen Sequence: GI # 7705753, sequence 1-245

Application

Anti-C1QA antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Complement C1q subcomponent subunit A is a protein encoded by the C1QA gene in humans. Anti-C1q antibodies are found to be pathogenic in the target organ damage of many autoimmune diseases, by facilitating C1q deposition and enhancing complement activation through classical pathway. It is also found to be associated with glomerular basement membrane (GBM) disease and in the pathogenesis of lupus. C1q deficiency leads to the development of autoimmune pathology throughout the life. C1q-binding protein participates in C1q-mediated chemotaxis of blood immune cells.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

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