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ANTI-CASPASE 1 ANTIBODY PRODUCED IN RABBIT

Sigma Aldrich

Catalog No.
C15-1731-176
Manufacturer No.
SAB5700660-100UL
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
EA
Price: $757.80
List Price: $842.00

General description This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.

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General description

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-311 of human Caspase-1 (NP_150635.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

UPC:
41116126
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
SAB5700660-100UL
Product Size:
100/µL

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