General description
CD45 is a receptor-tyrosine phosphatase required for antigen-induced signaling in T-cells and B-cells; its substrates are unknown. Interestingly, it associates with several Src-family tyrosine kinases, which are inhibited by tyrosine phosphorylation in their c-termini, suggesting a mechanism for signaling by CD45.
Specificity
Reactivity with other species has not been determined.
This antibody reacts with all isoforms of mouse CD45 which is expressed on all haematopoietic cells except erythrocytes.
FUSION PARTNER: SP2/0 myeloma cell line
Immunogen
Mouse lymph node cells.
Application
Anti-CD45 Antibody, clone IBL-5/25 is an antibody against CD45 for use in FC, IH.
Flow Cytometry Analysis: A previous lot detected CD45, clone IBL-5/25 in mouse peripheral blood lymphocytes
Quality
Evaluated by Immunohistochemistry in mouse colon tissue.
Immunohistochemistry Analysis: 1:100 dilution of this antibody detected CD45 in mouse colon tissue.
Target description
Approx. 147 kDa
Linkage
Replaces: CBL1326
Physical form
Format: Purified
Purified rat monoclonal IgG in phosphate buffered saline containing 10 mM sodium azide.
Storage and Stability
Store at 2-8°C for 12 months from date of receipt.
Analysis Note
Control
Mouse colon tissue
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Shipping Information:
Dry Ice Surcharge & Ice Pack Shipments: $40
More Information: https://cenmed.com/shipping-returns
- UPC:
- 41116128
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 05-1416
- Temperature Control Device:
- Yes
