General description

CDNF is a trophic factor for dopamine neurons. CDNF prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, CDNF restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.

Immunogen

Synthetic peptide directed towards the N-terminal region of Human CDNF

Sequence

Synthetic peptide located within the following region: IDRGVNFSLDTIEKELISFCLDTKGKENRLCYYLGATKDAATKILSEVTR

Physical form

Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.