General description
Cell death activator CIDE-A (CIDE-A) binds to lipid droplets and regulates their enlargement which restricts lipolysis and favoring storage. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. CIDE-A is highly expressed in brown adipose tissue and, at lower levels, in white adipose tissue.
Specificity
This antibody recognizes the C-terminus of CIDE-A.
Immunogen
Epitope: C-terminus
KLH-conjugated linear peptide corresponding to the C-terminus of mouse CIDE-A.
Application
Detect CIDE-A using this rabbit polyclonal antibody, Anti-CIDE-A Antibody validated for use in western blotting, IHC & Immunofluorescence.
Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected CIDE-A in mouse heart tissue.
Immunofluorescence Analysis: 20 µg/mL from a representative lot detected CIDE-A in mouse heart tissue.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Quality
Evaluated by Western Blotting in mouse heart tissue lysate.
Western Blotting Analysis: A 1:500 dilution of this antibody detected CIDE-A in 15 µg of mouse heart tissue lysate.
Target description
~25 kDa observed
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Mouse heart tissue lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: mouse. technique(s): immunofluorescence: suitable, immunohistochemistry: suitable, western blot: suitable. UniProt accession no.: O70302. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: mouse ... Cidea(12683). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable.Shipping Information:
Dry Ice Surcharge & Ice Pack Shipments: $40
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- UPC:
- 41105337
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- ABC350
- Temperature Control Device:
- Yes