General description
Circadian Locomotor Output Cycles Kaput, or Clock is a gene which encodes proteins regulating circadian rhythm. This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like protein to activate transcription of mouse period 1.
Specificity
Cat. # AB2203 recognizes CLOCK protein
Reactivity with other species has not been tested.
Application
Anti-CLOCK Antibody is an antibody against CLOCK for use in WB.
Western Blot Analysis:
L6 lysate was resolved by electrophoresis, transferred to PVDF membrane and probed with anti-CLOCK (1:500 dilution of this lot).
Proteins were visualized using a Donkey anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system.
Quality
Routinely evaluated by western blot on L6 tissue lysate.
Target description
Approx. 95 kDa
Analysis Note
Control
L6 Cell Lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
GenBank is a registered trademark of United States Department of Health and Human Services
biological source: rabbit. Quality Level: 100. antibody form: serum. antibody product type: primary antibodies. clone: polyclonal. species reactivity: mouse, human, rat. manufacturer/tradename: Chemicon®. . technique(s): western blot: suitable. GenBank®. accession no.: AAC53200. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: mouse ... Clock(12753). Storage Class Code: 10 - Combustible liquids. WGK: WGK 1.- UPC:
- 41116126
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- AB2203
