General description
Beta Defensin-3 is a novel 5 kDa nonhemolytic antimicrobial protein peptide which may be important in the innate epithelial defense of infections by various microorganisms seen in skin and lung (such as cystic fibrosis).
Specificity
Recognizes the 5-6 kDa human Defensin-3, beta protein.
Immunogen
A synthetic peptide consisting of amino acids 23-33 [GIINTLQKYYC] of the human beta-defensin-3 protein.
Application
Anti-Defensin Antibody, β3 is an antibody against Defensin for use in ELISA & WB.
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Western blotting: Tricine-SDS- PAGE gels recommended: 1:500-1:1,000, migrates as a 5-6kDa band; Tricine-SDS-urea PAGE gels: Native Beta Defensin 3 migrates as a 9kDa band; the larger size is because of the reduction of the three cysteine bridges present in the peptide protein
Optimal working dilutions must be determined by the end user.
Physical form
Format: Purified
Purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.
Storage and Stability
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
biological source: rabbit. Quality Level: 100. antibody form: purified immunoglobulin. antibody product type: primary antibodies. clone: polyclonal. species reactivity: human. manufacturer/tradename: Chemicon®. . technique(s): ELISA: suitable, western blot: suitable. NCBI accession no.: NM_018661.3. UniProt accession no.: P81534. shipped in: dry ice. target post-translational modification: unmodified. Gene Information: human ... DEFB103A(414325), DEFB103B(414325). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51202902
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- AB3478