Anti-FABP1 Antibody (C15-1317-908)

General description

FABP1, also known as Fatty acid-binding protein, Liver Fatty acid-binding protein, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP, Squalene- and sterol-carrier protein, SCP, Z-protein, or p14, and encoded by the gene FABP1/FABPL, is an important fatty acid binding and transport protein. FABP1 is produced in the liver and is part of a family of lipid carrier proteins. FABP1 facilitate the transfer of fatty acids between extra and intracellular membranes. FABP1 level in the blood is used as a biomarker for obesity and type II diabetes. Additionally, recent research indicates that FABP1 can modulate stellate cell activation and this may lead to diet-induced nonalcoholic fatty liver disease, thus FABP1 is a key focus of metabolic research.

Immunogen

Recombinant protein corresponding to rat FABP1.

Application

Anti-FABP1 Antibody detects level of FABP1 & has been published & validated for use in FABP1.

Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected FABP1 in wild type mouse liver cytosol and not in LFABP-1 -/- mouse liver cytosol.

Quality

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected FABP1 in 10 µg of human liver tissue lysate.

Target description

~ 14 kDa observed

biological source: rabbit. Quality Level: 100. antibody form: serum. antibody product type: primary antibodies. clone: polyclonal. species reactivity: human, mouse. species reactivity (predicted by homology): rat (based on 100% sequence homology). technique(s): western blot: suitable. NCBI accession no.: NP_036688. UniProt accession no.: P02692. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: rat ... Fabp1(24360). Storage Class Code: 10 - Combustible liquids. WGK: WGK 1.