General description
Fibrillin-2 is a part of the Fibrillin family of glycoproteins, which are essential factors in the formation and maintenance of elastic fibers known as microfibrils within the extracellular matrix. Various researchers have suggested that Fibrillin-2 has a role in the mediation of microfibril assembly during early elastogenesis. Defects in Fibrillin-2 are causal to a rare disorder involving autosomal dominant connective tissue known as congenital contractual arachnodactyly (CCA), also known as Beals syndrome or distal arthrogryposis type 9 (DA9), and is similar to Marfan syndrome.
Specificity
The antibody recognizes Fibrillin-2.
Immunogen
Recombinant protein corresponding to human Fibrillin-2.
Application
Anti-Fibrillin-2 Antibody, clone 48 is an antibody against Fibrillin-2 for use in IH, ELISA, IP & IC.
ELISA Analysis: A previous lot was used by an independent laboratory in ELISA (Charbonneau, 2003).
Immunofluorescence Analysis: A previous lot was used by an independent laboratory in IF (Charbonneau, 2003).
Quality
Evaluated by Immunohistochemistry in liver cancer and papillary serous carcinoma paraffin-embedded tissue sections.
Immunohistochemistry Analysis: 1:50 dilution of this antibody detected Fibrillin-2 in paraffin-embedded tissue sections of liver cancer and papillary serous carcinoma.
Target description
~ 215 kDa
Physical form
Format: Purified
Analysis Note
Control
Liver cancer and papillary serous carcinoma tissue
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Shipping Information:
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- UPC:
- 51281647
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- MAB2642
- Temperature Control Device:
- Yes
