General description
FOXK2 belongs to the mammalian forkhead transcription factor family and contains forkhead DNA-binding domain and an FHA domain at the N-terminal region.
Immunogen
Synthetic peptide directed towards the C terminal region of human FOXK2
Application
Anti-FOXK2 (AB2) antibody produced in rabbit is suitable for western blotting at a concentration of 2.5 μg/ml.
Biochem/physiol Actions
FOXK2 plays an important regulatory role in AP-1 binding and AP-1 mediated gene expression. It has been identified as regulator of IL-2 transcription and is linked to cell cycle progression. FOXK2 reportedly binds to DNA containing G/T mismatches with high affinity.
Sequence
Synthetic peptide located within the following region: SASLPTKRHNGDQPEQPELKRIKTEDGEGIVIALSVDTPPAAVREKGVQN
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
- UPC:
- 12352200
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- AV100774-100UL
