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ANTI-GP120 ANTIBODY PRODUCED IN RABBIT (C15-1740-606)

Sigma Aldrich

Catalog No.
C15-1740-606
Manufacturer No.
SAB3501286-100UG
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
EA
Price: $780.44
List Price: $867.15

General description Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of

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General description

Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.

Immunogen

gp120 antibody was raised against a peptide corresponding to 15 amino acids near the center of HIV-1 gp120.

Application

gp120 antibody can be used for Western blot at 1 - 2 μg/mL.

Physical form

Supplied in PBS containing 0.02% sodium azide.

UPC:
51201516
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
SAB3501286-100UG
Product Size:
100/µG

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