General description
Interleukin-12 alpha (IL-12A) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit (CLMF p35), IL-12 subunit p35, or NK cell stimulatory factor chain 1 (NKSF-1). IL-12A is a cytokine that, along with IL12B, forms a disulfide-linked heterodimer interleukin IL-12. IL-12 alpha functions as a regulator of T cell mediated cytotoxicity, interferon-gamma production, lymphocyte proliferation and activation of natural killer cells.
Specificity
This antibody recognizes the near C-terminus of IL-12 alpha
Immunogen
KLH-conjugated linear peptide corresponding to the near C-terminus of human IL-12 alpha.
Application
Immunohistochemistry Analysis: A 1:16,000-32,000 dilution from a representative lot detected IL-12 alpha in human tonsil and human brain tissue.
This IL-12 alpha antibody is validated for use in WB & IHC for the detection of the IL-12 alpha protein.
Quality
Evaluated by Western Blotting in human lymph node tissue lysate.
Western Blotting Analysis: 0.2 µg/mL of this antibody detected IL-12 alpha in 10 µg of human lymph node tissue lysate.
Target description
~25 kDa observed
Linkage
Replaces: MABN1084
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: human. technique(s): immunohistochemistry: suitable (paraffin), western blot: suitable. NCBI accession no.: NP_000873. UniProt accession no.: P29459. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... IL12A(3592). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 12352203
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- ABN213
