General description
IL27RA (also known as Interleukin-27 receptor subunit alpha, Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor, TCCR and ZcytoR1) is a receptor for IL27 and requires IL6ST/gp130 to mediate signal transduction in response to IL27 binding. IL27RA is involved in the regulation of Th1-type immune responses and appears to be involved in innate defense mechanisms. IL27RA is predominately expressed in thymus, spleen, lymph nodes and peripheral blood leukocytes.
Immunogen
Epitope: N-terminus
KLH-conjugated linear peptide corresponding to amino acids near the N-terminus of human IL27RA.
Application
Anti-IL27RA Antibody is a highly specific rabbit polyclonal antibody, that targets IL27RA & has been tested in western blotting, IHC & Immunofluorescence.
Immunohistochemistry Analysis: 10 μg/mL from a representative lot detected IL27RA in human spleen tissue.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected IL27RA in A549 cells.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
Quality
Evaluated by Western Blotting in human spleen tissue lysate.
Western Blotting Analysis: 1 μg/mL of this antibody detected IL27RA in human spleen tissue lysate.
Target description
~69 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: human. technique(s): immunofluorescence: suitable, immunohistochemistry: suitable, western blot: suitable. UniProt accession no.: Q6UWB1. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... IL27RA(9466). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 12352203
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- ABF295