General description
Interleukin 3 receptor subunit α alpha (IL3RA or CD123) gene is localized in the X and Y chromosomes. It comprises a highly mobile N-terminal domain (NTD) region and fibronectin type III (FnIII) domain. CD123 is expressed on early hematopoietic cells and is a type I cytokine receptor.
Immunogen
Synthetic peptide of human interleukin 3 receptor, alpha (low affinity)
Biochem/physiol Actions
Elevated expression of IL3RA is reported in chronic myeloid leukemia (CML).) It may serve as a therapeutic potential to treat acute myelogenous leukemia (AML).
Features and Benefits
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Physical form
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- UPC:
- 51131728
- Condition:
- New
- Availability:
- 3-5 Dyas
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- SAB4301605-100UL
- Product Size:
- 100/µL