Anti-Integrin alpha 10 (ITGA10) Antibody (C15-1316-419)

General description

Integrins are transmembrane proteins that are involved in interactions cell-to-cell and cell-to-extracellular matrix (ECM) adhesion. Integrins play diverse roles including cell migration, development, wound healing, differentiation, and apoptosis. Integrin alpha 10 subunit (ITGA10), along with integrin beta 1, is thought to be an essential part of a novel collagen type II receptor expressed mainly in chondrocytes and cartilage tissue.

Specificity

Other homologies: rat (93% sequence homology).

This antibody recognizes the extracellular domain of Integrin alpha 10.

Immunogen

Epitope: Extracellular Domain

KLH-conjugated linear peptide corresponding to the extracellular domain of human Integrin alpha-10.

Application

Detect Integrin alpha 10 (ITGA10) using this Anti-Integrin alpha 10 (ITGA10) Antibody validated for use in WB.

Research Category
Cell Structure

Research Sub Category
Integrins

Adhesion (CAMs)

Quality

Evaluated by Western Blot in SW-1353 cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected integrin alpha10 in 10 µg of SW-1353 cell lysate.

Target description

~127 kDa observed

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
SW-1353 cell lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: rhesus macaque, primate, human. species reactivity (predicted by homology): canine (based on 100% sequence homology), chimpanzee (based on 100% sequence homology), rhesus monkey (based on 100% sequence homology), pig (based on 100% sequence homology). technique(s): western blot: suitable. NCBI accession no.: NP_003628. UniProt accession no.: O75578. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... ITGA10(8515). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.