ANTI-INTEGRIN AV (AB-1) MOUSE MAB (272-17E6) (C005B-227749)

General description

Purified mouse monoclonal antibody. Recognizes the α_v integrin chain and all α_v-containing integrins.

Recognizes the α_v integrin chain and all α_v-containing integrins.

This Anti-Integrin α_v (Ab-1) Mouse mAb (272-17E6) is validated for use in Cell Inhibition Assays, ELISA, FC, IP for the detection of Integrin α_v (Ab-1).

Immunogen

Human

human placental α_vβ₃ integrin

Application

Cell Inhibition Assays (see application reference)

ELISA (see application reference)

Flow Cytometry (2.5 µg/ml, see application reference)

Immunoprecipitation (2.5 µg/ml, see application reference)

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In PBS, pH 7.6.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Akiyama, S.K. 1996. Hum. Cell9, 181.
Hynes, R.O. 1992. Cell69, 11.
Albelda, S.M. and Buck, C.A. 1990. FASEB J.4, 2868.
Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol.3, 179.
Hynes, R.O. 1987. Cell45, 549.

Cross-reacts with all α_v integrins. Blocks cell adhesion mediated by all α_v integrins and in vivo melanoma growth and angiogenesis (see application references). Variables associated with assay conditions will dictate the proper working dilution.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

biological source: mouse. Quality Level: 100. antibody form: purified antibody. antibody product type: primary antibodies. clone: 272-17E6, monoclonal. form: liquid. contains: ≤. 0.1% sodium azide as preservative. species reactivity: human. manufacturer/tradename: Calbiochem^®. . storage condition: OK to freeze, avoid repeated freeze/thaw cycles. isotype: IgG1. shipped in: wet ice. storage temp.: −. 20°C. target post-translational modification: unmodified. Gene Information: human ... ITGAV(3685). Storage Class Code: 10 - Combustible liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.

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