General description
Integrin beta-2, also known as CD18, is an adhesion receptor in neutrophils that interacts with cytohesin-1 intracellularly. Integrin beta is instrumental in activation-dependent adhesion and adhesion-dependent signaling. Expression of integrin beta-2 has a positive correlation with patient survival from malignant B cell lymphoma.
Immunogen
Whole B10 mouse spleen cells enriched with T-cells.
Application
Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP (Sanchez-Madrid, F., et al. (1983). J. ExP. MED. 158:586-602).
Inhibition Analysis: A previous lot of this antibody was shown to inhibit lymphoma metastasis (Zahalka, M. A. et al. (1993) J. Immunol. 150, 4466).
This Anti-Integrin beta-2 (CD18) Antibody, clone M18/2 is validated for use in FC, IP for the detection of Integrin beta-2 (CD18).
Quality
Evaluated by Flow Cytometry in mouse EL4 cells.
Flow Cytometry Analysis: 10 µg of this antibody detected Integrin beta-2 in mouse EL4 cells.
Target description
85 kDa calculated
Physical form
Format: Purified
Analysis Note
Control
Mouse EL4 cells
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Shipping Information:
Dry Ice Surcharge & Ice Pack Shipments: $40
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- UPC:
- 41116015
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- MABT42
- Temperature Control Device:
- Yes
![anti-integrin beta2 [cd18] antibody](https://cdn11.bigcommerce.com/s-2u2oi3cvy8/images/stencil/500x659/products/949417/777346/cenmed-product-image-placeholder-1-__66226.1717524908.jpg?c=1 "anti-integrin beta2 [cd18] antibody")
