Anti-Interleukin-8 Antibody (C15-1315-709)

General description

Interleukin-8 (IL-8) is a chemokine produced by macrophages, epithelial cells and endothelial cells. IL-8′s primary function is to recruit neutrophils to phagocytose the antigen which trigger the antigen pattern toll-like receptors. IL-8 can be secreted by any cells with toll-like receptors which are involved in a body’s innate immune response. Once IL-8 is secreted, it becomes an important mediator of immune reaction and inflammatory response. IL-8’s monomer and homodimer forms are both inducers of CXCR1 and CXCR2. IL-8 is also believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection.

Specificity

Reacts with human IL-8.
No reactivity to IL-1alpha, IL-1beta, IL-2, IL-3, IL4, IL-6, IL-7, IL-10, MIP-1alpha, TNFalpha, GM-CSF and IgG WHO standards by EIA.

Immunogen

Recombinant human IL-8.

Application

Anti-Interleukin-8 Antibody is an antibody against Interleukin-8 for use in ELISA & WB.

Research Category
Inflammation & Immunology

Research Sub Category
Cytokines & Cytokine Receptors

Western blot: A 1:1000-1:3000 dilution of anti-interleukin-8 (IL-8) detected recombinant human IL-8.

ELISA: A recommended dilution range of 1:100-1:1000 of anti-interleukin-8 (IL-8) was used on recombinant IL-8.

Final working dilutions must be determined by end user.

Quality

Routinely evaluated by western blot on recombinant human IL-8.

Target description

11 kDa

Physical form

Format: Purified

Liquid in PBS, no preservatives.

Protein A purified

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source: rabbit. Quality Level: 100. antibody form: purified antibody. antibody product type: primary antibodies. clone: polyclonal. species reactivity: human. manufacturer/tradename: Chemicon^®. . technique(s): ELISA: suitable, western blot: suitable. isotype: IgG. NCBI accession no.: NM_000584.2. UniProt accession no.: P10145. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... CXCL8(3576). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable.