Immunogen
Immunogen Sequence: GI # 10047128, sequence 280-375
Recombinant potassium channel modulatory factor
Application
Anti-KCMF1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
KCMF1 (DEBT91) is mapped to chromosome 2p11.2 in humans. It encodes a 381 amino acid molecule with high Ser and Thr composition and is highly conserved at its N-terminus across species. DEBT91 is suggested to be a coiled-coil nuclear phosphoprotein with zinc finger motifs at the N-terminal conserved region, which is rich in cysteine and histidine. It is an immediate early gene up-regulated during growth factor-induced branching tubulogenesis. DEBT91 plays an important role in gastric carcinogenesis. Its upregulation in response to bFGF in gastric cancer might be implicated in carcinogenesis through dysregulation of growth modulator.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
- UPC:
- 12352207
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- GW21213-50UG