General description
Mouse polyclonal antibody raised against a full-length human KIAA1456 protein. The gene KIAA1456 is mapped to human chromosome 8. It has an SAM (S-adenosyl methionine)-dependent methyltransferase domain.
Immunogen
KIAA1456 (NP_065895, 1 a.a. ~ 367 a.a) full-length human protein.
Sequence
MVCDNLNLPFRDEGFDAIISIGVIHHFSTKQRRIRAIKEMARVLVPGGQLMIYVWAMEQKNRRFEKQDVLVPWNRALCSQLFSESSQSGRKRQCGYPERGHPYHPPCSECSCSVCFKEQGGSKRSHSVGYEPAMARTCFANISKEGEEEYGFYSTLGKSFRSWFFSRSLDESTLRKQIERVRPLKNTEVWASSTVTVQPSRHSSLDFDHQEPFSTKEQSLDEEVFVESSSGKHLEWLRAPGTLKHLNGDHQGEMRRNGGGNFLDSTNTGVNCVDAGNIEDDNPSASKILRRISAVDSTDFNPDDTMSVEDPQTDVLDSTAFMRYYHVFREGELCSLLKENVSELRILSSGNDHGNWCIIAEKKGGCD
Biochem/physiol Actions
KIAA1456 might be involved in the regulation of the translation of specific protein(s) via the methyltransferase activity. It negatively regulates tumor growth and the mRNA is downregulated in breast, bladder, colorectal, cervical and testicular carcinomas.
Physical form
Solution in phosphate buffered saline, pH 7.4
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- UPC:
- 51111909
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- SAB1407796-50UG
- Temperature Control Device:
- Yes
