General description
KLF8 functions as a downstream target of focal adhesion kinase (FAK) during cell cycle progression and cyclin D1 regulation. It has also been implicated in oncogenic transformation. Furthermore, KLF8 is known to have prognostic implications in gastric adenocarcinomas.
Rabbit Anti-KLF8 (AB2) antibody recognizes human, mouse, and rat KLF8.
Immunogen
Synthetic peptide directed towards the middle region of human KLF8
Application
Rabbit Anti-KLF8 (AB2) antibody can be used for western blot applications at a concentration of 0.5μg/ml. It has also been used for immunohistochemistry applications.
Biochem/physiol Actions
KLF8 is abnormally expressed in female patients with X autosome translocation t(X;21)(p11.2;q22.3) and non-syndromic mental retardation.
Sequence
Synthetic peptide located within the following region: LEIPSDSEESTIESGSSALQSLQGLQQEPAAMAQMQGGESLDLKRRRIHQ
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
- UPC:
- 51282131
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- AV32859-100UL
