Anti-Ligand-dependent nuclear receptor-interacting factor 1 Antibody (C15-1316-837)

General description

Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1), also known as RIF1, Receptor-interacting factor 1, and is encoded by the gene LRIF1/C1orf103/RIF1. The retinoic acid receptors (RARs) are ligand-dependent transcription factors that play critical roles in cell differentiation, embryonic development, and tumor suppression. RAR transcriptional activities are mediated by a growing family of nuclear receptor (NR) coregulators. Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1) is such a coregulator. Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1) is a repressor of ligand-induced transcriptional activity of retinoic receptor alpha. Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1) is ubiquitously expressed in a wide variety of tissues and cells and localizes exclusively to the nucleus and specifically to the nuclear matrix.

Immunogen

Epitope: Near C-terminus

KLH-conjugated linear peptide corresponding to a region near the C-terminus of human Ligand-dependent nuclear receptor-interacting factor 1.

Application

Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected Ligand-dependent nuclear receptor-interacting factor 1 in HeLa, A431, HepG2, and NIH/3T3 cells.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Chromatin Biology

This Anti-Ligand-dependent nuclear receptor-interacting factor 1 Antibody is validated for use in western blotting & ICC for the detection of Ligand-dependent nuclear receptor-interacting factor 1.

Quality

Evaluated by Western Blotting in SH-SY5Y cell lysate.

Western Blotting Analysis: A 1:2,000 dilution of this antibody detected Ligand-dependent nuclear receptor-interacting factor 1 in 10 µg of SH-SY5Y cell lysate.

Target description

~100 kDa observed

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: human, mouse. species reactivity (predicted by homology): primate (based on 100% sequence homology). concentration: 0.5 . mg/mL. technique(s): immunocytochemistry: suitable, western blot: suitable. NCBI accession no.: NP_060842. UniProt accession no.: Q5T3J3. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... LRIF1(55791). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.