General description

LYAR, also known as Ly1 antibody reactive clone, has been found to regulate the intracellular strength that is stimulated by both T and B cell antigen receptors. It is essential for immune tolerance and certain changes to its function could stimulate the development of autoreactivity. LYAR is important in the immunological synapse and functions to inhibit the T cell response. LYAR is highly expressed in indifferentiated embryonic stem cells and may be important in maintaining the stem cell identity.

Immunogen

GST-tagged recombinant protein corresponding to mouse LYAR.

Application

Anti-LYAR Antibody (Ly1 reactive clone) detects level of LYAR (Ly1 antibody reactive clone) & has been published & validated for use in WB.

Research Sub Category
Immunoglobulins & Immunology

Pluripotent & Early Differentiation

Quality

Evaluated by Western Blot in mouse embryonic stem cell lysate.

Western Blot Analysis: A 1:1,000 dilution of this antibody detected LYAR in 10 µg of mouse embryonic stem cell lysate.

Target description

~48 kDa observed

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: mouse. technique(s): western blot: suitable. NCBI accession no.: NP_079557. UniProt accession no.: Q08288. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: mouse ... Lyar(17089). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.