Immunogen
Immunogen Sequence: GI # 4505061, sequence 60-114
Recombinant cation-dependent mannose-6-phosphate receptor
Application
Anti-M6PR antibody produced in chicken is suitable for immunocytochemistry and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
Mannose 6-phosphate receptor is an integral transmembrane glycoprotein encoded by the M6PR gene in humans. It is ubiquitously expressed and are distinguished from all other lectins by their ability to recognize phosphorylated mannose residues. It is a 46kDa cation-dependent mannose 6-phosphate receptor (CD-MPR) and plays a key role in the delivery of lysosomal enzymes to the lysosome by binding newly synthesized mannose 6-phosphate (Man-6-P)-containing acid hydrolases and diverting them from the secretory pathway. M6PR plays a major role in cellular function by transporting Man-6-P-containing acid hydrolases from the Golgi to endosomal/lysosomal compartments.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
- UPC:
- 51201700
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- GW21444-50UG