ANTI-MAML1 ANTIBODY (C15-1315-787)

General description

Members of the evolutionarily conserved Mastermind (MAM) protein family, including the three related mammalian Mastermind-like (MAML) proteins MAML1–3, function as crucial coactivators of Notch-mediated transcriptional activation. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

Specificity

Cat. # AB15546 recognizes MAML1 protein.

Reactivity with other species has not been tested.

Immunogen

Synthetic Linear Peptide.

Application

MAML1 can be detected at 1/1000 dilution in 10 µg of HEK293 cell Lysate.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

This Anti-MAML1 Antibody is validated for use in WB for the detection of MAML1.

Quality

Routinely evaluated by immunoblot.

Target description

108 kDa

Physical form

Serum with 0.05% NaN₃

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 1 year after date of receipt.

Analysis Note

Control
Tested by Western Blot on HEK293 cell lysate.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source: rabbit. Quality Level: 100. antibody form: serum. antibody product type: primary antibodies. clone: polyclonal. species reactivity: human. manufacturer/tradename: Chemicon^®. . technique(s): western blot: suitable. UniProt accession no.: Q92585. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... MAML1(9794). Storage Class Code: 10 - Combustible liquids. WGK: WGK 1.