ANTI-MNX1 (HB9) ANTIBODY (C15-1317-463)

General description

Motor neuron and pancreas homeobox protein 1 (MNX1) is a transcription factor that is predominantly expressed in lymphoid and pancreatic tissues. It is involved in the development and function of the pancreas. Abnormal expression of MNX1 results in an autosomal dominant condition known as Currarino syndrome.

Specificity

Other homologies: Zebrafish (94% sequence homology) and Xenopus (89% sequence homology).

This antibody recognizes a portion of the Homeobox DNA binding domain.

Immunogen

KLH-conjugated linear peptide corresponding to human MNX1.

Application

Anti-MNX1 (HB9) Antibody detects level of MNX1 (HB9) & has been published & validated for use in Western Blotting & IHC.

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected MNX1 in human pancreas and mouse cerebral cortex tissues.

Research Category
Neuroscience

Research Sub Category
Transcription Factors

Quality

Evaluated by Western Blot in PANC-1 cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected MNX1 in 10 µg of PANC-1 cell lysate.

Target description

~50 kDa observed. An uncharacterized band may appear at ~48 kDa in some lysates.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
PANC-1 cell lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: mouse, human. technique(s): immunohistochemistry: suitable, western blot: suitable. NCBI accession no.: NP_005506. UniProt accession no.: P50219. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... MNX1(3110). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.