General description
Nanos homolog 1 (NANOS1, NOS-1) contains one nanos-type zinc finger and belongs to the nanos family. It is an RNA-binding protein that is predominantly expressed in testis during germline development. NANOS 1 is highly expressed in lung carcinomas that can be detected in invasive tumor cells. NANOS1 up-regulates the production of MMP14 to promote tumor cell invasion.
Specificity
This antibody recognizes the intermediate domain of NANOS1.
Immunogen
Epitope: Intermediate domain
KLH-conjugated linear peptide corresponding to the intermediate domain of human NANOS1.
Application
Detect Nanos homolog 1 using this rabbit polyclonal antibody, Anti-NANOS1 Antibody validated for use in western blotting & IHC.
Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected NANOS1 in human brain tissue.
Research Category
Cell Structure
Research Sub Category
Adhesion (CAMs)
Quality
Evaluated by Western Blotting in rat brain tissue lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected NANOS1 in 15 µg of rat brain tissue lysate.
Target description
~42 kDa observed
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Rat brain tissue lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: rat, human. technique(s): immunohistochemistry: suitable, western blot: suitable. UniProt accession no.: Q8WY41. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... NANOS1(340719). Storage Class Code: 10 - Combustible liquids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 41116126
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- ABT337