General description
The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumors. It is widely expressed and most abundant in heart and skeletal muscle. NIPSNAP proteins have been suggested to be important in vesicular transport.
Specificity
NIPSNAP2 antibody is predicted to not cross-react with any other members of the NIPSNAP protein family.
Immunogen
KLH-conjugated linear peptide corresponding to human NIPSNAP2.
Application
Detect the NIPSNAP2 protein using this Anti-NIPSNAP2 validated for use in WB & IHC.
Immunohistochemistry Analysis: 2.5µg/mL of this antibody from a representative lot detected NIPSNAP2 in mouse skeletal muscle tissue.
Quality
Evaluated by Western Blot in human skeletal muscle tissue lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected NIPSNAP2 in 15 µg of human skeletal muscle tissue lysate.
Target description
~31 kDa observed
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: human, mouse. technique(s): immunohistochemistry: suitable, western blot: suitable. UniProt accession no.: O75323. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... GBAS(2631). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 41116113
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- ABN354
