General description
In skeletal muscles, Pax7 uniquely marks muscle satellite cells and plays some important yet unknown functions at the perinatal stage. Pax3/7BP is a ubiquitously expressed nuclear protein, enriched in Pax7+ muscle precursor cells (MPCs), and serves as an indispensable adaptor for Pax7 to recruit the histone-3-lysine-4 (H3K4) methyltransferase (HMT) complex by bridging Pax7 and Wdr5. Recently, Wu et al. have established Pax3/7BP as an essential adaptor linking Pax3/7 with the H3K4 HMT to regulate the proliferation of muscle progenitor cells.
Immunogen
Recombinant protein corresponding to mouse PAX3/7BP.
Application
Anti-PAX3/7BP Antibody is an antibody against PAX3/7BP for use in western blotting & IP.
Research Category
Stem Cell Research
Research Sub Category
Muscle Physiology
Developmental Signaling
Quality
Evaluated by Western Blot in a jurkat cell lysate.
Western Blot Analysis: A 1:1000 dilution of this antibody detected Pax3/7BP in a 10 µg jurkat cell lysate.
Target description
~105 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physical form
Unpurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
biological source: rabbit. Quality Level: 100. antibody form: serum. antibody product type: primary antibodies. clone: polyclonal. species reactivity: rat, mouse, human. technique(s): immunoprecipitation (IP): suitable, western blot: suitable. UniProt accession no.: Q9Y5B6. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: mouse ... Paxbp1(67367). Storage Class Code: 10 - Combustible liquids. WGK: WGK 1.Shipping Information:
Dry Ice Surcharge & Ice Pack Shipments: $40
More Information: https://cenmed.com/shipping-returns
- UPC:
- 51183306
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- ABD85
- Temperature Control Device:
- Yes
