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anti-pdp2 antibody produced in mouse

ANTI-PDP2 (C15-1749-247)

Sigma Aldrich

Catalog No.
C15-1749-247
Manufacturer No.
SAB1407792-50UG
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
EA
Price: $980.46
List Price: $1,089.40

General description Mouse polyclonal antibody raised against a full-length human PDP2 protein. PDP2 (Pyruvate dehyrogenase phosphatase catalytic subunit 2) is a mitochondrial serine phos­phatase consisting of a catalytic subunit (PDP2c).

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General description

Mouse polyclonal antibody raised against a full-length human PDP2 protein.

PDP2 (Pyruvate dehyrogenase phosphatase catalytic subunit 2) is a mitochondrial serine phos­phatase consisting of a catalytic subunit (PDP2c). It is a Mg2+ dependent enzyme. It has two active isoforms PDP 1 and 2. It is expressed in mammalian mitochondria.

Immunogen

PDP2 (NP_065837.1, 1 a.a. ~ 529 a.a) full-length human protein.

Sequence
MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLCKAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPVEDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESMKPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDSDISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIGNNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG

Application

Anti-PDP2 antibody produced in mouse is suitable for western blot analysis.

Biochem/physiol Actions

PDP2 (Pyruvate dehyrogenase phosphatase catalytic subunit 2) is indirectly associated with glycolysis and the tricarboxylic acid cycle and fatty acid (FA) synthesis. It is an Mg2+ dependent enzyme. PDP2 is mainly involved in the activation of phosphorylated pyruvate dehydrogenase complex (PDC), which is an essential component for the stimulation of the oxidative decarboxylation of pyruvate.

Physical form

Solution in phosphate buffered saline, pH 7.4

UPC:
41181942
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
SAB1407792-50UG
Product Size:
50/µG

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