General description
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.
Immunogen
Recombinant protein of human PHGDH.
Physical form
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Shipping Information:
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- UPC:
- 41141606
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- SAB5701384-100UL
- Temperature Control Device:
- Yes
