General description
The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Immunogen
A phospho synthetic peptide corresponding to residues surrounding S420 of Mouse CGAS.
Physical form
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Shipping Information:
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- UPC:
- 41106614
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- SAB5701957-100UL
- Temperature Control Device:
- Yes
