General description
Hormone sensitive lipase (HSL) is coded by LIPE (lipase E) gene. The gene coding for a protein is mapped on human chromosome 19q13. The encoded protein is an intracellular lipase with various neutral lipid substrates, such as triglycerides, diglycerides, monoglycerides, cholesterol esters and retinyl esters. HSL is widely expressed.
Immunogen
The antiserum was produced against synthesized peptide derived from human HSL around the phosphorylation site of Ser855/554.
Immunogen Range: 520-569
Biochem/physiol Actions
Hormone sensitive lipase (HSL) plays an important role in various processes such as lipolysis, adipocytes, steroidogenesis and spermatogenesis. Deficiency of HSL contributes to histologic abnormalities in white adipose tissue and an increase in macrophage infiltration. Polymorphism in the gene has been observed in familial lipodystrophies patients.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- UPC:
- 41181879
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- SAB4503821-100UG
- Product Size:
- 100/µG