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ANTI-PHOSPHO-MCM2-S139 ANTIBODY PRODUCED IN RABBIT

Sigma Aldrich

Catalog No.
C15-1729-903
Manufacturer No.
SAB5701937-100UL
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
EA
Price: $880.26
List Price: $978.07

General description The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM

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General description

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

Immunogen

A synthetic phosphorylated peptide around S139 of human MCM2.

Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

UPC:
12352203
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
SAB5701937-100UL
Product Size:
1/EA

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