Immunogen
Peptide sequence around phosphorylation site of serine 343 (S-L-S(p)-Q-G), according to the protein NBN.
Features and Benefits
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Target description
Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
Shipping Information:
Dry Ice Surcharge & Ice Pack Shipments: $40
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- UPC:
- 12352200
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- SAB4300045-100UG
- Temperature Control Device:
- Yes
