General description
PIASz is a members of the PIAS (protein inhibitor of activated signal transducer and activator of transcription) family of proteins, negative regulators of the Janus family of tyrosine kinase (JAK)-signal transducer and activator of transcription pathway. PIAS proteins have been shown to act as transcriptional co-regulators of multiple signaling pathways in various cellular processes. PIASz increases ligand-dependent transcriptional activity of androgen receptor and other nuclear hormone receptors, possibly through alteration of chromatin structure by SWI/SNF-like BAF complexes
Immunogen
PIASZ1 (NP_113637, 344-380)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PIASz1.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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- UPC:
- 51183703
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- SAB1300524-100UG
- Temperature Control Device:
- Yes