Anti-PPARgamma antibody produced in chicken

Immunogen

Immunogen Sequence: GI # 4826930, sequence 1-110

Recombinant peroxisome proliferative activated receptor gamma, isoform 1

Application

Anti-PPARγ antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Biochem/physiol Actions

Peroxisome proliferator-activated receptor γ(PPAR-γ or PPARG) is a type II nuclear receptor encoded by the PPARG gene in humans. PPARs are ligand-activated transcription factors of the nuclear hormone receptor superfamily. PPARγ is expressed as two isoforms, PPARγ2 and PPARγ1. PPARγ2 is expressed at high levels in the adipose tissues, whereas PPARγ1 has a broader expression pattern. PPARγ2 in skeletal muscle can promote conversion of subcutaneous fat to brown fat formation leading to increased energy metabolisms and combating obesity. PPARγ mRNA is expressed in humans in spleen, bone marrow, liver, testis, skeletal muscle and brain, in addition to fat.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.