General description
PR domain proteins (PRDMs) have been associated with many types of human cancers. PRDM14 was found to be up-regulated in breast cancer cells. The expression of PRDM14 to breast cancer cells actually increased cell proliferation and decreased the effect of chemotherapeutic drugs, while down-regulation of PRDM14 did the opposite. In addition to breast cancer, PRDM14 has recently been linked to non-small cell lung cancer development. PRDM14 also seems to play a role in the preservation of the self-renewal of human embryonic stem cells and transcriptional regulation.
Specificity
This antibody recognizes the N-terminus of PRDM14.
Immunogen
GST-tagged recombinant protein corresponding to the N-terminus of human PRDM14.
Application
This Anti-PRDM14 Antibody is validated for use in WB for the detection of PRDM14.
Quality
Evaluated by Western Blot in human lung tissue lysate.
Western Blot Analysis: A 1:1000 dilution of this antibody detected PRDM14 in 10 µg of human lung tissue lysate.
Target description
~62 kDa observed
biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: rat, mouse, human. technique(s): western blot: suitable. NCBI accession no.: NP_078780. UniProt accession no.: Q9GZV8. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... PRDM14(63978). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.Shipping Information:
Dry Ice Surcharge & Ice Pack Shipments: $40
More Information: https://cenmed.com/shipping-returns
- UPC:
- 41106508
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- AB4350
- Temperature Control Device:
- Yes
