General description
Prohibitin is an inhibitor of DNA synthesis that is widely expressed across various tissues. Prohibitin influences proliferation, and may also have a role in regulating mitochondrial respiration activity and in aging. Expression levels of prohibitin in fibroblasts have been found to decrease heterogeneously as cellular aging occurs.
Specificity
Other homologies: Mouse (86% sequence homology).
This antibody recognizes Prohibitin near the N-Terminus.
Immunogen
KLH-conjugated linear peptide corresponding to human Prohibitin near the N-Terminus.
Application
Detect Prohibitin using this rabbit polyclonal antibody, Anti-Prohibitin Antibody validated for use in western blotting & IHC (Paraffin).
Immunohistochemistry Analysis: A 1:100-500 dilution from a representative lot detected Prohibitin in human kidney and human ileum tissue.
Quality
Evaluated by Western Blotting in human liver tissue lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected Prohibitin in 10 µg of human liver tissue lysate.
Target description
~32 kDa observed
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: human. species reactivity (predicted by homology): rat (based on 100% sequence homology), canine (based on 100% sequence homology), bovine (based on 100% sequence homology). technique(s): immunohistochemistry: suitable (paraffin), western blot: suitable. NCBI accession no.: NP_002625. UniProt accession no.: P35232. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... PHB(5245). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.Shipping Information:
Dry Ice Surcharge & Ice Pack Shipments: $40
More Information: https://cenmed.com/shipping-returns
- UPC:
- 41105329
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- ABN293
- Temperature Control Device:
- Yes
